Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope...
Found on
http://en.wikipedia.org/wiki/Monoclonal_antibody
Antibody produced by cloned cells derived from a single
lymphocyte.
Found on
http://sis.nlm.nih.gov/enviro/iupacglossary/glossarym.html
antibody produced artificially by a genetic engineering technique. Production of monoclonal antibodies was one of the most important techniques of ... [7 related articles]
Found on
http://www.britannica.com/eb/a-z/m/113
A type of protein made in the laboratory that can bind to substances in the body, including tumor cells. There are many kinds of monoclonal antibodies. Each monoclonal antibody is made to find one substance. Monoclonal antibodies are being used to treat some types of cancer and are being studied in the treatment of other types. They can be used alo...
Found on
http://www.cancer.gov/dictionary?expand=M
<immunology, molecular biology> A substance, usually a protein, which can be synthsised in the laboratory in pure form by a single clone (population) of cells. ... These antibodies can be made in large quantities and have a specific affinity for certain target molecules called antigens which can be found on the surface of cells and those that...
Found on
http://www.encyclo.co.uk/local/20973
An extremely pure antibody derived from a single clone of an antibody-producing cell. Invading pathogens, viral or bacterial, carry a large number of different antigens each capable of stimulating the host's immune system to generate a corresponding antibody. A single spleen cell exposed to a specific antigen can be fused with a myeloma (cancer) cell. The resultant fused cell, called a hybridoma, continually produces an antibody specifically directed against the antigen. It will therefore seek out and identify the specific antigen. Hybridomas can be cloned and cultured to produce quantities of the pure 'monoclonal antibody'. Because of its specificity each monoclonal antibody may be used for diagnostic or therapeutic purposes. Most research and development has employed mouse antibodies grown in the peritoneal cavity of immuno-suppressed mice. Specific diagnostic tools which allow the rapid detection of individual proteins produced by the cells....
Found on
http://www.encyclo.co.uk/visitor-contributions.php
A protein that recognizes and attacks one specific foreign substance invading the body (antigen). A monoclonal antibody may be used for early disease diagnosis and therapy. See fusion. Monoculture Producing only one type of crop over a large area of farmland.
Found on
http://www.encyclo.co.uk/visitor-contributions.php
(MAB, MoAb) Type: Term Definitions: 1. an antibody produced by a clone or genetically homogeneous population of fused hybrid cells, hybridoma. Hybrid cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=4749
Monoclonal antibody: An antibody produced by a single clone of cells (specifically, a single clone of hybridoma cells) and therefore a single pure homogeneous type of antibody. Monoclonal antibodies can be made in large amounts in the laboratory and are a cornerstone of immunology. The term 'monoclonal' pertains to a single clone of cells, a single...
Found on
http://www.medterms.com/script/main/art.asp?articlekey=4425
An artificially produced antibody, made in the lab by use of an immortalized cell line. Monoclonal antibodies bind to one unique epitope.
Found on
http://www.virology.net/ATVGlossary.html
custom-made, identical antibody that recognizes only one epitope.
Found on
https://aidsinfo.nih.gov/news/128/hiv-vaccine-glossary
Click images to enlargeAntibody produced by fusing an antibody-producing lymphocyte (white blood cell) with a cancerous myeloma (bone-marrow) cell. The resulting fused cell, called a hybridoma, is immortal and can be used to produce large quantities of a single, specific antibody. By choosing antibodies that are d...
Found on
https://www.encyclo.co.uk/local/21221
A term used to describe a homologous Ig produced by a clone of B cells.
Found on
https://www.encyclo.co.uk/local/22445
The term used to describe a homologous Ig produced by a clone of B cells. This occurs naturally in neoplasia of B cells resulting in myeloma.
Found on
https://www.encyclo.co.uk/local/22445
antibody produced by a laboratory-grown cell clone, either of a hybridoma or a virus-transformed lymphocyte, that is more abundant and uniform than natural antibody and is able to bind specifically to a single site on almost any chosen antigen or reveal previously unknown antigen sites: used as an analytic tool in scientific research and medical......
Found on
https://www.infoplease.com/dictionary/monoclonal-antibody
custom-made, identical antibody that recognizes only one epitope of an antigen. These antibodies are used during controlled malaria challenge trials to validate target antigens that hold promise for preventing infection and transmission.
Found on
https://www.malariavaccine.org/glossary
No exact match found.
